Mrs. Frisby is a mouse and a mother of four children. She has a very hard time trying to help her youngest son Timothy survive pneumonia. When she finds out that Timothy is sick, she searches everywhere to find help. Moving day is coming soon and Mrs. Frisby is frantically working to solve her problem. Caring and working, for her children is a big responsibility because her husband Jonathan Frisby died. It is a very hard thing for her to manage, but she can do it.